

Supportive evidence from electromyography, genetic testing, and neuroimaging Genetic risk factors age male sex heavy metals organic chemicals smoking electric shock physical exercise head injury Ĭlinical diagnosis of exclusion based on progressive symptoms of upper and lower motor neuron degeneration in which no other explanation can be found. Later: Difficulty in speaking, swallowing, and breathing respiratory failure 10-15% experience frontotemporal dementia įalling (accident) Respiratory failure Pneumonia Malnutrition Parts of the nervous system affected by ALS, causing progressive symptoms in skeletal muscles throughout the body Įarly: Stiff muscles, muscle twitches, gradual increasing weakness,
